Ukwehla kwesisindo okuphindaphindiwe kanye nokubuyiselwa kwesisindo, okwaziwa ngokuthi umphumela we-yo-yo, kuvame ukuhlolwa ngesikali kuphela. Kodwa-ke, ucwaningo lwamuva lubonisa ukuthi lo mjikelezo ungashiya uphawu olungabonakali emisipheni. Ucwaningo, olwenziwe ochwepheshe e-University of California, eSan Francisco (UCSF) futhi lwanyatheliswa kuyi- Radiology , lubonisa ukuthi abantu ababhekana nokuguquguquka kwesisindo njalo bangase balahlekelwe kakhulu yimisipha kunalabo abalondoloza isisindo esizinzile.
Lolu cwaningo lulandele abantu abadala abangu-1.433 iminyaka emine, abaneminyaka ephakathi kuka-61, bonke ababhalise kwi-Osteoarthritis Initiative, iphrojekthi yase-US ehlaziya ingozi ye-osteoarthritis yamadolo. Besebenzisa i-magnetic resonance imaging (MRI), ososayensi bahlola ukwakheka komzimba wabahlanganyeli, benaka kakhulu umthamo wemisipha yamathanga kanye nenani lamafutha agcinwe kuleyo ndawo.
Ukuxhumana okucacile phakathi kokuguquguquka kwesisindo nokulahlekelwa yimisipha
Lapho abahlanganyeli behlukaniswa ngokwezinga lokuqina kwesisindo, imiphumela yabonisa umehluko ophawulekayo. Labo ababhekane nemijikelezo yokwehla kwesisindo futhi baphinde bathola isisindo sabo babone ukwehla okungu-3,71% komthamo wemisipha yethanga , kanti eqenjini elinesisindo esizinzile, ukwehla kwaba ngu-1,03% kuphela. Lokhu kuhlangana kwahlala ngisho nangemva kokulungisa iminyaka, ubulili, inkomba yesisindo somzimba eyisisekelo, izinga lomsebenzi womzimba, kanye nemikhuba yokudla.
Okutholwe okuhlaba umxhwele kakhulu ukuthi, ekupheleni kwesikhathi sokulandelela, womabili amaqembu ayenesisindo esifanayo nesisindo sawo sokuqala. Isikali sabonisa ukuzinza, kodwa ukwakheka komzimba wawo kwakuhlukile . Abacwaningi, beholwa uSolwazi we-Radiology uThomas Link, bakhomba ukuthi ngesikhathi sokushintshashintsha kwesisindo, abantu balahlekelwa izicubu zemisipha kanye namafutha, futhi abazange baphinde bazithole lapho bephinda bethola isisindo.
Lokhu okutholakele kugcizelela ukubaluleka kokungagxili esisindweni kuphela. Ukulahlekelwa isisindo esincane kungathinta amandla, ukuhamba, kanye nempilo ye-metabolic , ikakhulukazi eminyakeni ephakathi, lapho ukugcina isisindo semisipha esanele kubalulekile ekuvimbeleni ubuthakathaka kanye nokugcina ukuzimela.
Ukuhumusha ngokuqapha imiphumela
Naphezu kokubaluleka kwalokhu okutholakele, abalobi batusa ukuthi baqaphele. Lolu ucwaningo lokubuka, ngakho-ke lukhomba ubudlelwano kodwa alusunguli ubudlelwano obuqondile bembangela. Bangu -77 kuphela kwabangu-1.433 ababambiqhaza abahlukaniswe eqenjini lokujikeleza isisindo , futhi isampula ivela ocwaningweni olugxile kubantu abasengozini ye-osteoarthritis, ngakho-ke imiphumela ingase ingabi yinto evamile kubo bonke abantu.
Ubufakazi mayelana nemiphumela yesikhathi eside yokudla kwe-yo-yo buyaqhubeka nokuguquka. Ezinye zezingozi ezisolwayo ze-metabolic ezihlobene nalezi zindlela zokudla zisaphikiswana ngazo emphakathini wesayensi. Noma kunjalo, lolu cwaningo lunikeza ulwazi olufanele: ukwehlisa isisindo akubandakanyi nje ukulahlekelwa amafutha, kodwa futhi kungabandakanya ukwehla kwesisindo semisipha, futhi lokhu kulahlekelwa akubonakali njalo esikalini.
Ngale kwesisindo: ukwakheka komzimba njengesibonakaliso
Ucwaningo lwe-UCSF luphakamisa inkinga ebalulekile ngesikhathi lapho amasu okulwa nokukhuluphala efinyelela ukwehla kwesisindo okukhulu ngokwengeziwe. Impumelelo yokudla akufanele ilinganiswe kuphela ngenani lamakhilogremu alahlekile , kodwa kunalokho ngokushintsha kwamafutha, imisipha, nezinye izinkomba zezempilo.
Abacwaningi basebenzise ubuhlakani bokwenziwa ukuze bahlaziye ama-MRI scan ngokunemba okukhulu, okubavumela ukuthi bahlole hhayi nje kuphela umthamo wemisipha kodwa namafutha angene ngaphakathi kwemisipha futhi aqongelelene edolweni. Abantu ababili bangaba nesisindo esifanayo futhi babe nokwakheka komzimba okuhluke kakhulu , futhi lokhu kuthinta impilo yabo kanye namandla abo okusebenza.
Ngamazwi kaThomas Link, ukwehla kwamafutha kumane nje kuyisici esisodwa sephazili enkulu kakhulu. Ukulondoloza imisipha ngesikhathi sokunciphisa isisindo kufanele kube yinto eza kuqala , ikakhulukazi njengoba sikhula. Ucwaningo lwesikhathi esizayo luzodinga ukuqinisekisa ukuthi yimaphi amasu asiza ukugcina isisindo sinciphile ngenkathi sinciphisa isisindo.
Ngamafuphi, lolu cwaningo lusikhumbuza ukuthi ukushintshashintsha kwesisindo okuphindaphindiwe kungaba nemiphumela engaphezu kwalokho okubonakalayo. Ukulondoloza imisipha kubaluleke njengokulahlekelwa amafutha , futhi ukudla okunempilo kungaba ukulimaza lowo mgomo ngaphandle kokuthi siqaphele.